Abstract: A hybrid ¹⁸F-FDG positron emission tomography and computed tomography (¹⁸F-FDG PET-CT) image can offer the functional and anatomic information simultaneously. Compared with conventional methods, such as CT, EUS, it has advantages in determining the TNM staging, especially in measuring the length of primary tumor and detecting the metastasis of distant lymph nodes and organs. Moreover, it can guide the treatment and evaluate therapeutic effect of esophageal carcinoma.