国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (12): 930-933.doi: 10.3760/cma.j.issn.1673-422X.2014.12.016

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植物素抗胰腺癌的作用机制

  

  1. 解放军兰州空军机关医院外科(党军强),放射科(李长彬);空军工程大学信息与导航学院门诊部(陈媛、林文)
  • 出版日期:2014-12-24 发布日期:2015-02-02
  • 通讯作者: 李长彬,Email:jddjq12@126.com

Mechanism of phytochemicals as anticancer agents in parcreatic carcinoma

  1. Department of Surgery, Air Force Institution Hospital of Lanzhou, Lanzhou 730020, China
  • Online:2014-12-24 Published:2015-02-02
  • Contact: Li Changbin, Email: jddjq12@126.com

摘要: 胰腺癌是恶性程度很高的肿瘤,5年生存率低于5%。随着诊疗技术的进步, 胰腺癌患者症状得到了极大的改善,但其预后仍不乐观。近年来,来自于自然界的抗肿瘤植物得到了广泛关注。大量的实验室研究和临床试验表明姜黄素、异硫氰酸盐类、辣椒辣素、儿茶素等植物相关产品同降低肿瘤发病率之间有密切的相关性。

关键词: 姜黄素, 异硫氰酸盐类, 辣椒辣素, 儿茶素, 胰腺肿瘤

Abstract: Pancreatic cancer remains a devastating disease with a 5year survival rate of less than 5%. Recent advances in diagnostic methods and therapeutic approaches have increased the possibility of improving the existing poorprognosis. Recently, compounds from naturalsources receive ample attention as anticancer agents. Overwhelming in vitro evidence and clinical trials suggest that curcuminn, isothiocyanate, capsaicin, catechin may reduce the incidence of cancer.

Key words: Curcumin, Isothiocyanate, Capsaicin, Catechin, Pancreatic neoplasms