国际肿瘤学杂志 ›› 2025, Vol. 52 ›› Issue (1): 43-47.doi: 10.3760/cma.j.cn371439-20240528-00006

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pT2-3N0M0期胸段食管鳞状细胞癌治疗策略及预后影响因素研究进展

余洋1, 唐仕敏2, 杨露2, 李娜2()   

  1. 1川北医学院临床医学系,南充 637000
    2四川省遂宁市中心医院肿瘤中心,遂宁 629000
  • 收稿日期:2024-05-28 修回日期:2024-11-26 出版日期:2025-01-08 发布日期:2025-01-21
  • 通讯作者: 李娜 E-mail:lny.yl@163.com
  • 基金资助:
    四川省重点研发项目(2023YFS0488);遂宁市中心医院科研课题(2022ypj03)

Research progress in treatment strategies and prognostic factors for stage pT2-3N0M0 thoracic esophageal squamous cell carcinoma

Yu Yang1, Tang Shimin2, Yang Lu2, Li Na2()   

  1. 1Department of Clinical Medicine, North Sichuan Medical College, Nanchong 637000, China
    2Department of Cancer Center, Suining Central Hospital of Sichuan Province, Suining 629000, China
  • Received:2024-05-28 Revised:2024-11-26 Online:2025-01-08 Published:2025-01-21
  • Contact: Li Na E-mail:lny.yl@163.com
  • Supported by:
    Sichuan Key R&D Program(2023YFS0488);Research Topic of Suining Central Hospital(2022ypj03)

摘要:

pT2-3N0M0期胸段食管鳞状细胞癌患者虽然分期较早,但术后局部复发及远处转移率较高,导致此类患者5年生存率较低,并且目前此类患者的新辅助治疗仍处在研究阶段,术后是否予以辅助放化疗仍存在争议。此外,pT2-3N0M0期胸段食管鳞状细胞癌患者的预后影响因素尚未明确,复发与转移的原因尚不清楚。因此,明确治疗策略及探索预后影响因素对提高此类患者的生存率有重要意义,有望为pT2-3N0M0期胸段食管鳞状细胞癌患者改善预后、提高生存率提供新方向。

关键词: 食道鳞癌, 肿瘤治疗方案, 预后

Abstract:

Although patients with stage pT2-3N0M0 thoracic esophageal squamous cell carcinoma are staged earlier, their postoperative local recurrence and distant metastasis rates are higher, resulting in a low five-year survival rate of such patients. The current neoadjuvant treatment for such patients is still in the research stage, and whether to give adjuvant radiotherapy and chemotherapy after surgery is still controversial. In addition, the prognostic factors of patients with pT2-3N0M0 thoracic esophageal squamous cell carcinoma have not yet been clarified, and the causes of recurrence and metastasis are not yet clear. Therefore, it is of great significance to clarify treatment strategies and explore the impact of prognostic factors on improving the survival rate of such patients, which is expected to provide new directions for improving the prognosis and survival rate of patients with pT2-3N0M0 thoracic esophageal squamous cell carcinoma.

Key words: Esophageal squamous cell carcinoma, Antineoplastic protocols, Prognosis