国际肿瘤学杂志 ›› 2016, Vol. 43 ›› Issue (12): 940-942.doi: 10.3760/cma.j.issn.1673422X.2016.12.015

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Notch1基因与食管鳞状细胞癌

张蕾, 李多杰   

  1. 蚌埠医学院第一附属医院肿瘤放疗科
  • 出版日期:2016-12-08 发布日期:2016-11-02

Notch1 1 gene in esophageal squamous cell carcinoma

ZHANG  Lei, LI  Duo-Jie   

  1. Department of Radiation Oncology, First Affiliated Hospital of Bengbu Medical University, Bengbu 233000, China
  • Online:2016-12-08 Published:2016-11-02

摘要: 研究证实Notch1在食管鳞状细胞癌中呈低表达,起抑癌基因作用。研究Notch1基因与淋巴结转移、生存率之间的关系可以为食管鳞状细胞癌的治疗及预后评估提供更多有价值的帮助。

关键词: 受体, Notch1, 食管肿瘤, 癌, 鳞状细胞, 淋巴转移

Abstract: It is confirmed that Notch1 gene is low expressed in esophageal squamous cell carcinoma, which plays a tumor suppressor gene role. Researches about the relationships between Notch1 gene and lymph node metastasis and survival rate can provide more valuable help for the treatment and prognosis evaluation of esophageal squamous cell carcinoma.

Key words: Receptor, Nocth1, Esophageal neoplasms, Carcinoma, squamous cell, Lymphatic metastasis