国际肿瘤学杂志 ›› 2015, Vol. 42 ›› Issue (4): 288-291.doi: 10.3760/cma.j.issn.1673-422X.2015.04.013

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人乳头状瘤病毒相关头颈部鳞状细胞癌的研究进展

  

  1. 650500 昆明医科大学第三附属医院头颈外科
  • 出版日期:2015-04-08 发布日期:2015-04-22
  • 通讯作者: 费继敏,Email: jiminfei2015@163.com

Research advances of human papillomavirus-related head and neck squamous cell carcinoma

  1. Department of Head and Neck Surgery, the Third Affiliated Hospital of Kunming Medical College, Kunming 650500, China
  • Online:2015-04-08 Published:2015-04-22
  • Contact: Fei Jimin, Email: jiminfei2015@163.com

摘要: 近年来,人乳头状瘤病毒(HPV)相关头颈部鳞状细胞癌的发病率呈上升趋势,尤其表现在口腔鳞状细胞癌中。HPV相关头颈部鳞状细胞癌具有独特的临床特征、生物学特点及良好预后,且不暴露于吸烟、饮酒等危险因素,其生物标记物及治疗是国际的研究热点。

关键词: 头颈部肿瘤; 癌, 鳞状细胞; 人类; 乳头状瘤病毒科

Abstract: 【Abstract】Recently, the prevalence of human papillomavirus(HPV) infection in head and neck squamous cancers has shown an upward trend, especially in the oropharynx squamous carcinoma. This subset of head and neck cancers possesses distinct clinical and laboratory features and outcome, and is particulary common in individuals who lack the traditional risk factors of tobacco and alcohol abuse. The biological markers and treatment of HPV associated head neck cancers are hot topic in current international research.

Key words: Head and neck neoplasms, Carcinoma, squamous cell, Humans, Papillomaviridae