关键词: 吸烟, 肺肿瘤, 临床特点, 生存分析

Abstract: Objective To discuss the clinical characteristics and the relationship with the survival of smoking lung cancer patients. Methods The clinical data of 368 cases were retrospectively analyzed by comparing the differences of the age, gender, histological type, clinical stage, treatment and symptoms of tradition Chinese medicine, and their correlation with the survival was analyzed. Results: Among the 368 patients, the ones aged between 50 to 69 accounted for 69.84%; the proportion between the male ones and the female ones was 7.98:1; the proportion of the squamous cell carcinoma was as high as 52.45%; the proportion of the patients with small cell lung cancer in extensive stage was significantly higher than that of the patients in the limited stage(75.38% vs 24.62%); the numbers of the patients with non-small cell lung cancer in stage Ⅲ and Ⅳ was significantly higher than that in the stageⅠandⅡ(82.77% vs 17.23%); the ones with non-surgical treatment  accounted for 76.36%, and  the proportion of ones with surgery treatment were 23.64%; most of the patients were treated by both Chinese medicine and chemotherapy(41.04%); the main types of all patients were qi-yin deficiency syndrome and toxic heat flourishing syndrome, accounting for 36.96% and 29.28% respectively. The age（F=10.356，P=0.000）, clinical stage（F=11.289，P=0.000）, treatment methods（t=2.624，P=0.021）, smoking index（F=3.681，P=0.021） were the key factors effecting the survival (P＜0.05), and the gender, histological type, tradition Chinese medicine type had no significant effect（P＞0.05）.Conclusion The clinical characteristics of the cases are 50-69-aged, male, squamous cell carcinoma, advanced stage, treatment without surgery. The survival of smoking lung cancer patients is effected by the age, clinical stage, treatment methods and smoking index.

Key words: Lung neoplasms, Smoking, Clinical characteristics, Survival analysis