国际肿瘤学杂志

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侵袭性T细胞非霍奇金淋巴瘤的化疗

陈玉, 顾康生   

  1. 合肥,安徽医科大学第一附属医院肿瘤内科
  • 出版日期:2011-08-08 发布日期:2011-08-29
  • 通讯作者: 陈玉* E-mail:chenyu2109@126.com

Chemotherapy in aggressive T-cell non-Hodgkin lymphoma

CHEN  Yu, GU  Kang-Sheng   

  • Online:2011-08-08 Published:2011-08-29

摘要: T细胞非霍奇金淋巴瘤是一组具有独特临床和病理特征的疾病,与B细胞淋巴瘤相比,侵袭性更强,化疗敏感性差。为探索有效的治疗方案,近年来,新的药物(如吉西他滨、pralatrexate等)、靶向药物联合化疗及高剂量化疗联合造血干细胞移植被研究用于治疗T细胞淋巴瘤,并取得了一些进展。

关键词: 淋巴瘤, T细胞, 化学疗法

Abstract: T-cell non-Hodgkin lymphoma is a group disease with unique clinical and pathological features,compared with B-cell lymphoma,more aggressive, and lower chemotherapy sensitivity.In recent years,to explore high efficiency and light therapy adverse reactions chemotherapy,novel agents(such as gemcitabine ,pralatrexate and so on), targeted therapy combined with chemotherapy and high-dose chemotherapy combined with hematopoietic stem cell transplantation are studied for the treatment,and made some progress.

Key words: Lymphoma, T-cell, Chemotherapy