国际肿瘤学杂志

国际肿瘤学杂志 ›› 2011, Vol. 38 ›› Issue (10): 797-800.

• 论著 • 上一篇    

弥散张量成像在脑肿瘤中的应用

李伟, 龙晚生, 罗学毛, 等   

  • 出版日期:2011-10-08 发布日期:2011-09-27

Application of diffusion tensor imaging in brain tumors

LI  Wei, LONG  Wan-Sheng, LUO  Xue-Mao, et al    

  1. 江门市中心医院放射科
  • Online:2011-10-08 Published:2011-09-27

PDF

1784

被引次数

10

摘要： 目的 探讨脑肿瘤弥散张量成像(DTI)的特点及其在脑肿瘤中的诊断和鉴别诊断价值。方法 对39例经病理证实的脑肿瘤患者(脑膜瘤10例，胶质瘤17例，转移瘤12例)，采用Philips Achieva 1.5 T磁共振行常规MRI和DTI，在工作站上重建部分各向异性(FA)图、表观弥散系数(ADC)图和三维白质纤维束图，选择肿瘤核心实质区和对侧镜像区为兴趣区，测量FA和ADC值，并进行t检验，以P＜0.05为差异有统计学意义。结果  脑膜瘤、转移瘤和胶质瘤的FA值分别为0.36±0.08、0.28±0.03、0.18±0.06，即脑膜瘤最高，其次是转移瘤，而胶质瘤最低；FA值在脑膜瘤与转移瘤、脑膜瘤与胶质瘤、转移瘤与胶质瘤之间差异均有统计学意义(P＜0.05)。脑膜瘤、转移瘤和胶质瘤的ADC值分别为1.72±0.10、1.52±0.22、1.34±0.14，即脑膜瘤最高，其次是转移瘤，而胶质瘤最低；ADC值在脑膜瘤与转移瘤、脑膜瘤与胶质瘤、转移瘤与胶质瘤之间差异均有统计学意义(P＜0.05)。结论 DTI对脑膜瘤、转移瘤和胶质瘤的鉴别具有很高的临床价值。

关键词: font-size: 12pt, mso-bidi-font-family: 'Times New Roman', mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-font-kerning: 1.0pt, mso-ascii-font-family: 'Times New Roman', mso-hansi-font-family: 'Times New Roman'">磁共振成像font-size: 12pt, mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-font-kerning: 1.0pt, mso-fareast-font-family: 宋体" lang="EN-US">, font-size: 12pt, mso-bidi-font-family: 'Times New Roman', mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-font-kerning: 1.0pt, mso-ascii-font-family: 'Times New Roman', mso-hansi-font-family: 'Times New Roman'">弥散, 脑肿瘤

Abstract: Objective  To study the characteristics of diffusion tensor imaging (DTI) in brain tumor and it's diagnosis and differential diagnosis value. Methods  Thirty-nine patients with brain tumors proven by pathologically (10 meningioma, 17 glioma, 12 metastatic tumors), using Philips Achieva 1.5 T MRI, conventional MRI and DTI were underwent on them, fractional anisotropy (FA) maps, apparent diffusion coefficient (ADC) maps and three dimensional white matter fiber bundle map were reconstructed in the workstation, selected the core substance of the tumor area and the contralateral mirror area as the region of interest, measured FA and ADC values of them, and t test was performed, P＜0.05 was regarded as the difference have statistically significant. Results  The FA values of meningioma, metastases tumors and gliomas were 0.36±0.08, 0.28±0.03, 0.18±0.06, respectively, meningioma is the highest, followed by metastases tumors, and gliomas is the lowest. FA values between meningiomas and metastases tumors, meningiomas and gliomas, metastases tumors and gliomas had significant differences (P＜0.05). The ADC values of meningioma, metastases tumors and gliomas were 1.72±0.10, 1.52±0.22, 1.34±0.14, respectively, meningioma is the highest, followed by metastases tumors, and gliomas is the lowest. ADC values between meningiomas and metastases tumors, meningiomas and gliomas, metastases tumors and gliomas had significant differences (P＜0.05). Conclusion DTI has high clinical value in identification of meningiomas, metastatic tumors and glioma.

Key words: font-size: 12pt, mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-fareast-font-family: 宋体" lang="EN-US">Diffusion magnetic resonance imagingfont-size: 12pt, mso-bidi-font-family: 'Times New Roman', mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-ascii-font-family: 'Times New Roman', mso-hansi-font-family: 'Times New Roman'">, font-size: 12pt, mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-fareast-font-family: 宋体" lang="EN-US">Brain neoplasms