国际肿瘤学杂志

国际肿瘤学杂志 ›› 2011, Vol. 38 ›› Issue (10): 774-776.

• 综述 • 上一篇    下一篇

食管癌侵袭转移的分子生物学标志物

范小玲, 刘文其   

  1. 530007 南宁， 广西医科大学第一附属医院放疗科
  • 出版日期:2011-10-08 发布日期:2011-09-27
  • 通讯作者: 通信作者：刘文其，E-mail: liuwenqi999@yahoo.com.cn E-mail:liuwenqi999@yahoo.com.cn

Biological markers of esophageal carcinoma invasion and metastasis

FAN  Xiao-Ling, LIU  Wen-Qi   

  1. Department of Radiation Oncology,First Aiffiated Hospital Guangxi Medical University, Nanning 530007,China
  • Online:2011-10-08 Published:2011-09-27
  • Contact: Corresponding auther: LIU Wen-qi, E-mail: liuwenqi999@yahoo.com.cn E-mail:liuwenqi999@yahoo.com.cn

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摘要： 食管癌的侵袭转移与肿瘤发生发展的多个肿瘤标志物有关，其中包括基质金属蛋白酶、细胞黏附因子CD44、垂体瘤转化基因等。研究表明，这些肿瘤标志物均在食管癌中过表达，影响着食管癌的进展及预后，但其特异性及临床应用价值还有待进一步研究。

Abstract: The invasion and metastasis of esophageal carcinoma is associated with several tumor marker on   oncogenesi and tumor development, including matrix metalloproteinase, cell adhesion molecules CD44,pituitary-tumour transforming genes.Studies have shown that these tumor markera are over-expression in esophageal carcinoma, which affect the progress and prognosis of esophageal carcinoma , and their specificity and value for clinical application need to be futher studied