国际肿瘤学杂志

国际肿瘤学杂志 ›› 2011, Vol. 38 ›› Issue (10): 764-767.

• 综述 • 上一篇    下一篇

18F-脱氧葡萄糖PET-CT预测局部晚期非小细胞肺癌的疗效

祝守慧, 于甬华, 张永   

  1. 250117济南，山东省肿瘤医院放疗二病区
  • 出版日期:2011-10-08 发布日期:2011-09-27
  • 通讯作者: 于甬华，E-mail:sdwufx@163.com E-mail:sdwufx@163.com

Prediction of response to chemotherapy and (or) radiotherapy in locally advanced non–small cell lung cancer with 18F-FDG PET-CT

ZHU  Shou-Hui, YU  Yong-Hua, ZHANG  Yong   

  1. Department of Radiation Oncology, Shandong Cancer Hospital, Jinan 250117, China
  • Online:2011-10-08 Published:2011-09-27

PDF

1641

摘要： 18F-脱氧葡萄糖(18F-FDG)正电子发射断层显像(PET)-计算机断层成像(CT)已广泛用于非小细胞肺癌(NSCLC)的诊断、分期和疗效评价，特别对局部晚期NSCLC疗效预测具有重要价值。它可以动态观察肿瘤组织的代谢，根据治疗前后肿瘤组织对18F-FDG的摄取变化，通过可视或定量分析，在临床或亚临床水平达到早期预测局部晚期NSCLC放化疗疗效的目的。

Abstract: 18F-FDG PET-CT has been widely used for the diagnosis, staging and assessment of therapeutic response in patients with non-small cell lung cancer (NSCLC). In particular, the technique plays an important role in the prediction of the response to therapy in patients with locally advanced NSCLC. It can dynamically observe the tumor tissue metabolism, and according to the changes of 18F-FDG uptake by visual or quantitative analysis, before and after treatment, allow prediction of the early efficacy of locally advanced NSCLC with chemotherapy and (or) radiotherapy in clinical or sub-clinical levels.