国际肿瘤学杂志 ›› 2015, Vol. 42 ›› Issue (5): 361-363.doi: 10.3760/cma.j.issn.1673422X.2015.05.011

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异常剪接组织因子与肿瘤的关系

  

  1. 苏州大学附属第一医院血液科 江苏省血液研究所 卫生部血栓与止血重点实验室 血液学协同创新中心
  • 出版日期:2015-05-08 发布日期:2015-05-12
  • 通讯作者: 张日 zhang_r_i@163.com

Relation between alternatively spliced tissue factor and tumor

  1. Department of Hematology, First Affiliated Hospital of Soochow University, Hematology Institute of Jiangsu, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Collaborative Innovation Center of Hematology
  • Online:2015-05-08 Published:2015-05-12
  • Contact: Zhang Ri zhang_r_i@163.com

摘要: 丝氨酸/精氨酸富集蛋白(SR)、SR蛋白激酶等参与了异常剪接组织因子(asTF)的形成,近年发现asTF在肿瘤新生血管形成和肿瘤进展、转移等病理过程中发挥着一定的作用,在临床上对其检测将具有很大的意义。

Abstract: Serine/aginine rich (SR) protein, SR protein kinase and other enzymes participate in the composition of alternatively spliced tissue factor (asTF). Recently researchers have found that this protein takes a part in tumor angiogenesis, tumor progression, metastasis and so on, so the detection of its clinical content will be very significant.