PDCD5与肿瘤的临床相关性

doi:10.3760/cma.j.issn.1673422X.2015.05.009

国际肿瘤学杂志 ›› 2015, Vol. 42 ›› Issue (5): 355-357.doi: 10.3760/cma.j.issn.1673422X.2015.05.009

PDCD5与肿瘤的临床相关性

河北医科大学基础医学院临床医学专业

出版日期:2015-05-08 发布日期:2015-05-12
通讯作者: 刘伟 pkulw@aliyun.com
基金资助:
河北省科技厅项目（13397703D）;河北省科技厅应用基础研究计划重点基础研究项目（14967719D）;中华医学会医学教育分会项目（2012FF81）;河北省高等教育学会项目（GJXH2013135）

Clinical relativity of PDCD5 with tumor

Clinical Medicine Science, School of Basic Medicine

Online:2015-05-08 Published:2015-05-12
Contact: Liu Wei pkulw@aliyun.com

摘要/Abstract

摘要： 程序性细胞死亡因子5(PDCD5）是一种新的程序性细胞死亡调控基因。PDCD5表达广泛，进化保守，具有促进肺癌、肝癌等多种肿瘤细胞凋亡和抑制细胞增殖的效应。PDCD5在疾病情况下，特别是在肿瘤细胞中的表达明显下调，与肿瘤有着密不可分的临床相关性，对肿瘤的发现、诊断和治疗有很大的临床检验价值。

Abstract: Programmed cell death 5 (PDCD5） is a new kind of programmed cell death regulation and control gene. PDCD5's expression is widespread, and evolution is conservative. PDCD5 has the effect of promoting a wide variety of tumor cells to apoptosis and inhibiting proliferation, such as lung cancer, liver cancer et al. Several laboratories' discoveries show that PDCD5's expression is significantly decreased when in some disease cases, especially in tumor cases. PDCD5, which is related to the clinical relevance of the tumor, has a great clinical value of discovering, diagnosis and treatment of the tumor.

周振, 简杰坤, 王祯宝, 胡洁, 刘伟. PDCD5与肿瘤的临床相关性[J]. 国际肿瘤学杂志, 2015, 42(5): 355-357.

ZHOU Zhen, JIAN Jie-Kun, WANG Zhen-Bao, HU Jie, LIU Wei. Clinical relativity of PDCD5 with tumor[J]. Journal of International Oncology, 2015, 42(5): 355-357.

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PDCD5与肿瘤的临床相关性

Clinical relativity of PDCD5 with tumor

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