非编码小RNA与黑色素瘤

doi:10.3760/cma.j.issn.1673-422X.2017.07.016

国际肿瘤学杂志 ›› 2017, Vol. 44 ›› Issue (7): 541-543.doi: 10.3760/cma.j.issn.1673-422X.2017.07.016

非编码小RNA与黑色素瘤

柴莉，康晓静

830001 乌鲁木齐，新疆医科大学研究生学院（柴莉）；新疆维吾尔自治区人民医院皮肤性病科（柴莉、康晓静）

收稿日期:2017-02-21 出版日期:2017-07-08 发布日期:2017-06-20
通讯作者: 康晓静 E-mail:drkangxj666@163.com
基金资助:
新疆维吾尔自治区自然科学基金（2016D01C101）

Non-coding small RNA and melanoma

Chai Li, Kang Xiaojing

Graduate School of Xinjiang Medical University; Department of Dermatology and Venereology, People′s Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China

Received:2017-02-21 Online:2017-07-08 Published:2017-06-20
Contact: Kang Xiaojing E-mail:drkangxj666@163.com
Supported by:
Natural Science Foundation of Xinjiang Uygur Autonomous Region of China (2016D01C101)

摘要/Abstract

摘要： 【摘要】非编码小RNA主要包括微小RNA、小干扰RNA及与PIWI蛋白相作用的RNA。研究表明，非编码小RNA在表观遗传学的调控中扮演了越来越重要的角色。非编码小RNA在基因转录、基因转录后、mRNA翻译等多种水平参与了基因表达的调控，与人类多种疾病，特别是与黑色素瘤的诊断、治疗和预后评估密切相关。

关键词: 黑色素瘤, 非编码小RNA

Abstract: Non-coding small RNA mainly includes microRNA, small interfering RNA and RNA interacting with PIWI protein. Studies have shown that non-coding small RNA plays an increasingly important role in the epigenetic regulation. Non-coding small RNA is involved in the regulation of gene expression by gene transcription, posttranscription and mRNA translation. Non-coding small RNA is closely related to many human diseases, especially the diagnosis, treatment and prognosis of melanoma.

Key words: Melanoma, Non-coding small RNA

柴莉，康晓静. 非编码小RNA与黑色素瘤[J]. 国际肿瘤学杂志, 2017, 44(7): 541-543.

Chai Li, Kang Xiaojing. Non-coding small RNA and melanoma[J]. Journal of International Oncology, 2017, 44(7): 541-543.

参考文献

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非编码小RNA与黑色素瘤

Non-coding small RNA and melanoma

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