Abstract: Circulating endothelial cells（CECs）are mature endothelial cells, which have been shed from the vascular cell lining and enter into blood circulation. Rare in healthy individuals, increased CECs in peripheral blood reflects significant vascular damage and dysfunction. Increased CECs have been documented in many human diseasescharacterized as vascular damage, including different types of tumors. Clinical data suggest that CECs count is a promising tool for monitoring disease activity with potential to assess tumor prognosis and response to treatment.

Key words: color: black, font-size: 10.5pt, mso-font-kerning: 1.0pt, mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-fareast-font-family: 宋体, mso-bidi-font-size: 12.0pt" lang="EN-US">Neovascularization, pathologic, color: black, font-size: 10.5pt, mso-font-kerning: 1.0pt, mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-fareast-font-family: 宋体, mso-bidi-font-size: 12.0pt" lang="EN-US">Tumor markers, biological, color: black, font-size: 10.5pt, mso-font-kerning: 1.0pt, mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-fareast-font-family: 宋体, mso-bidi-font-size: 12.0pt" lang="EN-US">Circulating endothelial cells