Abstract: Intensity-modulated radiation therapy(IMRT)is a more advanced radiotherapy technique than routine radiotherapy, and has been effectively utilized in the treatment of nasopharyngeal carcinoma(NPC). Rradiotherapy alone has disappointing effect to local advanced cases．Nevertheless，chemoradiotherapy provides long term survival. Chemoradiotherapy is becoming the standard therapeutic regimen for local advanced NPC. But different ways of chemomdiotherapy such as induction，concurrent，adjuvant chemotherapy still need to be defined.