Journal of International Oncology ›› 2024, Vol. 51 ›› Issue (12): 789-793.doi: 10.3760/cma.j.cn371439-20240608-00134

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Research progress in the treatment of bone metastasis in lung cancer

Yu Degang1, Jia Junmei2()   

  1. 1First Medical College, Shanxi Medical University, Taiyuan 030001, China
    2Department of Respiratory Oncology, First Hospital of Shanxi Medical University, Taiyuan 030001, China
  • Received:2024-06-08 Revised:2024-07-19 Online:2024-12-08 Published:2025-01-07
  • Contact: Jia Junmei E-mail:jiajunmei1972@163.com

Abstract:

Bone metastasis of lung cancer is relatively common in patients with advanced lung cancer, the treatment research of which has been made remarkable progress. In terms of systemic therapy, chemotherapy is the traditional treatment plan; targeted therapy shows strong efficacy in treating lung cancer patients with specific gene mutations; immunotherapy can bring new treatment options for lung cancer patients with bone metastasis by activating the body's immune system, which can be used alone or in combination with other therapies. Anti bone metastasis drugs such as bisphosphonates and denosumab play an important role in reducing bone destruction and bone-related adverse events. In terms of local therapy, radiotherapy can accurately irradiate tumor lesions and relieve pain symptoms; surgical treatment is suitable for specific bone metastasis to restore bone stability and function. In addition, analgesic treatment and psychological intervention can alleviate patients' pain and anxiety. These therapeutic advances bring new hope to patients with lung cancer bone metastasis.

Key words: Lung neoplasms, Neoplasm metastasis, Therapy