Journal of International Oncology

Journal of International Oncology ›› 2012, Vol. 39 ›› Issue (3): 218-220.

Previous Articles     Next Articles

Application of epidermal growth factor receptor for radiotherapy of esophageal cancer

ZHANG  He-Ping, LI  Jian-Cheng   

  1. Department of Radiation Oncology, Affiliated Teaching Hospital of Fujian Medical University, Fujian Tumor Hospital, Fuzhou 350014, China
  • Online:2012-03-08 Published:2012-02-24
  • Contact: LI Jian-cheng, E-mail: jianchengLi6@126.com E-mail:jianchengLi6@126.com

PDF

1606

Abstract: Epidermal growth factor receptor (EGFR) express highly or mutant in esophageal cancer, which causing tumor resistance to radiotherapy and leading to poor radiotherapeutic effects. Treatment with anti-EGFR can get radiosensitization. There are three main types of molecular targeted research for EGFR: synthetic monoclonal antibody, small molecule tyrosine kinase inhibitors, and other strategies modulating EGFR biosynthesis based on RNA interference.

Key words:

line-height: 150%">color: black, line-height: 150%">Esophageal neoplasms, line-height: 150%, mso-bidi-font-size: 7.5pt">Receptor, epidermal growth factor, color: black, line-height: 150%">RNA interference