Journal of International Oncology ›› 2012, Vol. 39 ›› Issue (3): 193-196.

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Application of nanoparticle vectors in photodynamic therapy of tumors

SHI  Lei, WANG  Xiu-Li, WANG  Hong-Wei   

  1. SHI Lei, WANG Xiu-li, WANG Hong-wei. Shanghai Skin Disease Hospital Shanghai Clinical Institute of Skin and Venereal Disease, Anhui Medical University, Shanghai 200050, China
  • Online:2012-03-08 Published:2012-02-24

Abstract: For the past few years, with the extensive application of nanoparticle technology in photodynamic therapy (PDT) of cancers, there have been some improvements of the stability of photosensitizers, the tumor targeting, the working depth and the yield of singlet oxygen by a variety of ways. Furthermore, with nanoparticle, PDT also can be combined with some other treatments together. Finally, the use of nanoparticle vectors for PDT is a novel and promising approach which might improve the efficiency of photodynamic therapy for tumors, overcome many adverse effects and increase the indications of PDT.

Key words: color: black">Nanoparticles, color: black">Photochemotherapy, Neoplasms, text-decoration: none, text-underline: none">Photosensitizing agents