核黄素与胃癌

doi:10.3760/cma.j.issn.1673422X.2015.09.018

摘要/Abstract

摘要： 胃癌发病率及死亡率高，其综合治疗在临床上有重大意义。核黄素是一种水溶性维生素，由核黄素转运蛋白吸收利用，可以通过抑制肿瘤细胞的增殖及促进凋亡等方面发挥抗肿瘤作用。核黄素在胃癌发生、发展、治疗、侵袭转移及减轻放化疗不良反应方面起重要作用，研究其作用机制及生物学特征，有助于为胃癌患者制定更具体的个体化治疗方案。

Abstract: Gastric cancer incidence and morality are high, and its comprehensive treatment of gastric cancer has a major significance in clinical. Riboflavin is a watersoluble vitamin, absorbed by riboflavin transporter protein, which can perform antitumor function by inhibiting tumor cell prolifiration and inducing promoting apoptosis. Riboflavin plays importan roles in gastric cancer development, treatment, cancer invasion, metastasis and reducing the adverse effects of chemotherapy. Studying on mechanism and biological characterristic of riboflavin may help to develop more specific individualized treatment plans for the patients with gastric cancer in the future.

穆艾太尔·麦提努日, 玛依努尔·艾力. 核黄素与胃癌[J]. 国际肿瘤学杂志, 2015, 42(8): 706-.

MU Ai-Tai-尔·Mai-Ti-Nu-Ri, MA Yi-Nu-尔·Ai-Li. The plasma riboflavin level and gastric cancer[J]. Journal of International Oncology, 2015, 42(8): 706-.

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