国际肿瘤学杂志 ›› 2013, Vol. 40 ›› Issue (10): 778-781.

• 综述 • 上一篇    下一篇

老年晚期胃癌的化疗

夏宁俊, 张静, 田永立   

  1. 210029 南京中医药大学第一临床医学院(夏宁俊、张静);江苏省中医院肿瘤科(田永立)
  • 出版日期:2013-10-08 发布日期:2013-09-23
  • 通讯作者: 田永立,E-mail: tianyongli0007@126.com E-mail:tianyongli0007@126.com
  • 基金资助:

    江苏省高校优势学科建设工程(中西医结合)项目(苏政办发[2011]6号);江苏省中医药局2011年开放课题项目(JD11034)

Chemotherapy in elderly patients with advanced gastric cancer

XIA  Ning-Jun, ZHANG  Jing, TIAN  Yong-Li   

  1. First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210029, China
  • Online:2013-10-08 Published:2013-09-23
  • Contact: TIAN Yong-li, E-mail: tianyongli0007@126.com E-mail:tianyongli0007@126.com

摘要: 新一代口服氟尿嘧啶类衍生物卡培他滨和替吉奥(S-1)已广泛应用于老年患者的治疗,有一定疗效且不良反应较小。氟尿嘧啶类和铂类的联合方案或可提高疗效,但同时也增加了不良反应的发生。3药联合方案的临床报道较少,疗效尚不确切,明显了增加不良反应。

关键词: 胃肿瘤, 老年人, 化学疗法, 辅助

Abstract: New oral fluoropyrimidines, such as capecitabine and S-1, have been widely used for elderly patients with a certain efficiency and slight toxicity. Fluorouracil and platinum program probably enhances the effectiveness, but also increases the incidence of adverse reactions. There are a few clinical reports about triple-drug combination for elderly patients, but the efficacy is not certain and the toxicity is obvious.

Key words: Stomach neoplasms, Aged, Chemotherapy, adjuvant