国际肿瘤学杂志

国际肿瘤学杂志 ›› 2012, Vol. 39 ›› Issue (3): 228-230.

• 综述 • 上一篇    下一篇

幽门螺杆菌与大肠癌相关性研究进展

梁云佳, 储榆德, 戴德坚   

  1.  200235 上海市第八人民医院结直肠外科（梁云佳、戴德坚），胃肠专科（储榆德）

  • 出版日期:2012-03-08 发布日期:2012-02-24
  • 通讯作者: 戴德坚，E-mail:daidejian@hotmail.com E-mail:daidejian@hotmail.com

Helicobacter pylori and colorectal cancer

LIANG  Yun-Jia, CHU  Yu-De, DAI  De-Jian   

  1. Department of Colorectal Surgery, Eighth People’s Hospital of Shanghai, Shanghai 200235, China

  • Online:2012-03-08 Published:2012-02-24
  • Contact: DAI De-jian, E-mail: daidejian@hotmail.com E-mail:daidejian@hotmail.com

摘要： 幽门螺杆菌(Hp)感染与大肠癌之间关系的研究发现，大肠癌及其相关腺瘤患者的Hp感染率较高，提示Hp有可能通过自身毒力和升高血浆胃泌素水平等方式作用于局部和远处的大肠黏膜细胞致癌，Hp感染是大肠癌的一种潜在危险因素。

关键词: color: black, font-size: 12pt, mso-font-kerning: 1.0pt, mso-bidi-font-family: 'Times New Roman', mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA">螺杆菌, 幽门, 结直肠肿瘤

Abstract: Recent researches of the association between helicobacter pylori (Hp) and colorectal adenocarcinoma have found that Hp infection rate is higher in the patients with colorectal cancer and other related colorectal adenoma, which suggest that Hp probably influence on local and distant intestinal mucosa epithelial cells achieve carcinogenesis by its own virulence and the role of elevated serum gastrin levels. Hp infection may be a potential risk factor of colorectal cancer.

Key words: color: black, font-size: 12pt, mso-font-kerning: 1.0pt, mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-fareast-font-family: 宋体" lang="EN-US">Helicobacter pylori, color: black, font-size: 12pt, mso-font-kerning: 1.0pt, mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-fareast-font-family: 宋体" lang="EN-US">Colorectal neoplasms