国际肿瘤学杂志 ›› 2011, Vol. 38 ›› Issue (10): 790-793.

• 综述 • 上一篇    下一篇

微小RNA在卵巢癌中的作用

张春洁, 李娜, 金平   

  1. 730000 兰州 兰州大学第一临床医学院妇产科学
  • 出版日期:2011-10-08 发布日期:2011-09-27
  • 通讯作者: 金平,E-mail:pingjin66@sina.com E-mail:pingjin66@sina.com

Function of microRNAs in ovarian cancer

ZHANG  Chun-Jie, LI  Na, JIN  Ping   

  1. First Clinical Medical School, Lanzhou University, Lanzhou 730000, China
  • Online:2011-10-08 Published:2011-09-27
  • Contact: Corresponding author: JIN Ping, E-mail: pingjin66@sina.com E-mail:pingjin66@sina.com

摘要: 微小RNA(miRNA)在卵巢癌中表达明显改变。基于微阵列芯片检测的卵巢癌相关miRNA表达谱和后续的对个别miRNA的深入研究,发现其与卵巢癌的发生、发展、复发、耐药等密切相关,有望用于卵巢癌早期诊断、复发检测、预后判定及治疗。

Abstract: The expression of microRNAs (miRNAs) alters obviously in ovarian cancer. Through miRNA profile based on a microarray platform and further research on individual one, they are found to be closely related to pathogenesis, progression, recurrence, and drug resistance of ovarian cancer and have a good prospect in applying it in the early diagnosis, detection recurrence, prognosis and therapy of ovarian cancer.