国际肿瘤学杂志 ›› 2025, Vol. 52 ›› Issue (3): 176-179.doi: 10.3760/cma.j.cn371439-20240701-00027

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抗肿瘤药物递送系统研究进展

张百红1, 岳红云2()   

  1. 1中国人民解放军联勤保障部队第九四〇医院肿瘤科,兰州 730050
    2中国人民解放军联勤保障部队第九四〇医院眼科,兰州 730050
  • 收稿日期:2024-07-01 修回日期:2024-07-20 出版日期:2025-03-08 发布日期:2025-04-02
  • 通讯作者: 岳红云,Email:yhyophthalmologist@163.com
  • 基金资助:
    甘肃省自然科学基金(22JR5RA007);联勤保障部队第九四〇医院课题(2021yxky052)

Advances in anticancer drug delivery systems

Zhang Baihong1, Yue Hongyun2()   

  1. 1Department of Oncology,940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army,Lanzhou 730050,China
    2Department of Ophthalmology,940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army,Lanzhou 730050,China
  • Received:2024-07-01 Revised:2024-07-20 Online:2025-03-08 Published:2025-04-02
  • Contact: Yue Hongyun,Email:yhyophthalmologist@163.com
  • Supported by:
    Natural Science Foundation of Gansu Province of China(22JR5RA007);Research Subject of 940th Hospital of Joint Logistics Support Force(2021yxky052)

摘要:

药物递送系统(DDS)可以降低抗肿瘤药物的脱靶效应。抗肿瘤药物DDS的载体主要有纳米微粒、小分子、核酸、多肽和抗体以及细胞,它们通过连接器携载抗肿瘤药物,将药物递送至特异的肿瘤组织和细胞。DDS将推动肿瘤精准医学的发展。

关键词: 肿瘤, 治疗, 药物递送系统

Abstract:

Drug delivery system (DDS) holds promise in reducing off-target effects of antitumor drugs. The carriers of antitumor drug DDS mainly include nanoparticles,small molecules,nucleic acids,peptides,antibodies and cells,which carry antitumor drugs through linker to deliver the drugs to specific tumor tissues and cells. DDS will propel progress in the field of cancer precision medicine.

Key words: Neoplasms, Therapy, Drug delivery systems