临床指标在食管癌新辅助治疗疗效预测中的价值

doi:10.3760/cma.j.cn371439-20250415-00100

摘要/Abstract

摘要：

新辅助治疗是局部晚期可手术食管癌的首选治疗模式，其临床价值已通过循证医学证据而确立，在治疗前或治疗中准确鉴别出可获益患者，对于整体治疗策略的制定有重要意义。临床指标如年龄、性别、病理特征、营养状态、血液学/组织学指标对食管癌新辅助治疗疗效预测有一定价值，但单一指标预测疗效效果有限，需综合运用多种指标并结合先进的技术和方法，为临床疗效预测提供精准、实用的工具。

关键词: 食管肿瘤, 新辅助疗法, 疗效预测, 临床指标

Abstract:

Neoadjuvant therapy is the preferred treatment mode for locally advanced operable esophageal cancer， and its clinical value has been established through evidence-based medical evidence. Accurately identifying patients who can benefit before or during treatment is of great significance for formulating the overall treatment strategy. Clinical indicators such as age， gender， pathological characteristics， nutritional status， and hematological/histological indicators have certain value in predicting the efficacy of neoadjuvant therapy for esophageal cancer. However， the predictive effect of a single indicator is limited. It is necessary to comprehensively use multiple indicators and combine advanced technologies and methods to provide accurate and practical tools for clinical efficacy prediction.

Key words: Esophageal neoplasms, Neoadjuvant therapy, Response prediction, Clinical indicators

程红蕾, 王体, 兰志东, 巩合义. 临床指标在食管癌新辅助治疗疗效预测中的价值[J]. 国际肿瘤学杂志, 2025, 52(9): 592-597.

Cheng Honglei, Wang Ti, Lan Zhidong, Gong Heyi. Value of clinical indicators in predicting the efficacy of neoadjuvant therapy for esophageal cancer[J]. Journal of International Oncology, 2025, 52(9): 592-597.

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