国际肿瘤学杂志

国际肿瘤学杂志 ›› 2011, Vol. 38 ›› Issue (11): 854-857.

• 综述 • 上一篇    下一篇

微RNA与子宫内膜癌

梁静, 马本红, 张贵宇   

  1. 250012 山东大学齐鲁医院妇产科
  • 出版日期:2011-11-08 发布日期:2011-11-03
  • 基金资助:

    山东省科技攻关项目资助项目（2008GG1000205）

MiRNA and endometrial cancer

LIANG  Jing, MA  Ben-Hong, ZHANG  Gui-Yu   

  1. Department of Gynaecology and Obstetrics, Qilu Hospital of Shandong University, Jinan 250012, China
  • Online:2011-11-08 Published:2011-11-03

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被引次数

1

摘要： 微RNA（miRNA）参与了肿瘤发生等多种生命活动，应用分子生物学与信息生物学方法探讨miRNA在肿瘤发生中所起的作用是目前研究的热点。近年来多种在子宫内膜癌中有特异研究价值的miRNA被发现，其作用机制也被深入探讨，这些结果为子宫内膜癌发病机制的研究提供了有效的依据。

Abstract: MicroRNA is a class of non-protein coding, single-stranded small RNAs of 22-25 nucleotides length. It takes part in many physiological processes including tumorigenesis. In the present focus studis, molecular biology and bioinformatics methods are used to study the role of miRNA in endometrial carcinoma. Several miRNAs with research value have been found and their mechanisms have been investigated. Results from the studis provid valid evidence for further research.