Abstract: In surgical operation of the  non-small cell lung cancer  (NSCLC)，the resection of lymph node involvement is highly correlated with the prognosis of  NSCLC patients．The precise estimation of localized lymph node involved and the determination of relevant pattern of lymphadenectomy are the significant predictors for the prognosis and postoperative treatment in NSCLC patients． Therefore to identify the lymph node metastasis earlier has more important significance for tumor clinical staging and making therapeutic schedule．In recent years，the value of sentinel lymph node (SLN)has attracted more and more researchers attention in detecting the occult lymph node micrometastases and surgical staging.