Abstract: With the continuous development of tumor immunology, cancer vaccines have become a hot spot of tumor immunotherapy. Companion member antigen peptide tumor vaccine attracts widely attention because of its chemical stability, easy preparation and no carcinogenic potential advantage. Companion member antigen peptide tumor vaccine may work through many kinds of ways including the function of antigen presenting, enhancing the body's non-specific line of anti-tumor mechanisms and activating the tumor-specific immune mechanism. Its different anti-tumor mechanisms merits and so on will have positive function in the tumor clinical immunity treatment.