Abstract: Mammalian target of rapamycin (mTOR) plays an important role in the regulation of cell proliferation, growth, energy metabolism and so on. Clinical research demonstrate that many tumors have its excessive expression, and the mTOR inhibitors rapamycin can resist the development of gastric cancer. In recent years, research of mTOR signaling pathway combined with its upstream and downstream has larger value for the early diagnosis, monitoring curative effect and prognosis.

Key words: color: green, font-size: 12pt, mso-font-kerning: 1.0pt, mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-fareast-font-family: 宋体" lang="EN-US">Gastric neoplasms, color: green, font-size: 12pt, mso-font-kerning: 1.0pt, mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-fareast-font-family: 宋体" lang="EN-US">Mammalian target of rapamycin