国际肿瘤学杂志 ›› 2012, Vol. 39 ›› Issue (2): 96-98.

• 综述 • 上一篇    下一篇

滋养层细胞表面蛋白2及其在肿瘤中的表达

蒋海锋, 薄隽杰   

  1. 200001 上海交通大学医学院附属仁济医院泌尿外科
  • 出版日期:2012-02-08 发布日期:2012-01-18
  • 通讯作者: 薄隽杰,Email:bojuanjie@yahoo.com.cn E-mail:bojuanjie@yahoo.com.cn
  • 基金资助:

    上海市科学技术委员会科研计划项目(09ZR14180000)

Trophoblastic cell surface protein 2 and tumor

JIANG  Hai-Feng, BAO  Juan-Jie   

  1. Department of Urology, Renji Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200127, China
  • Online:2012-02-08 Published:2012-01-18
  • Contact: Corresponding author: BO Juan-jie, E-mail: bojuanjie@yahoo.com.cn E-mail:bojuanjie@yahoo.com.cn

摘要: 滋养层细胞表面蛋白2(TROP2)是一种细胞表面糖蛋白,因为在滋养层细胞表面高表达而得名。最近研究发现TROP2蛋白在很多人类上皮性肿瘤中也存在高表达,而且与患者的预后有关,但其具体的作用机制目前仍不清楚。      

Abstract: TROP2 (trophoblastic cell surface protein 2), a cell-surface glycoprotein, is named after its high expression only in trophoblast cells. Recent studies found that TROP2 protein is overexpressed in a variety of human epithelial cancers, and it is associated with the prognosis. However, the mechanism is still not clear.