国际肿瘤学杂志

国际肿瘤学杂志 ›› 2011, Vol. 38 ›› Issue (11): 836-838.

• 综述 • 上一篇    下一篇

微RNA与头颈鳞癌的研究进展

张康, 马静, 隋军, 等   

  1. 650118 昆明医学院第三附属医院（云南省肿瘤医院）头颈外科 云南省头颈肿瘤研究中心

  • 出版日期:2011-11-08 发布日期:2011-11-03
  • 通讯作者: 李晓江，xiaojiangle.@yahoo.com.cn E-mail:xiaojiangle.@yahoo.com.cn
  • 基金资助:

    云南省科技计划项目(2008CD036)

miRNA gene in head and neck cancer

ZHANG  Kang, MA  Jing, SUI  Jun, et al   

  1. Surgery Department of Head and Neck, Head and Neck Cancer Center of Yunnan Province, Third Affiliated Hospital of Kunming Medical College(Tumor Hospital of Yunnan Province). Kunming 650118, China
  • Online:2011-11-08 Published:2011-11-03
  • Contact: Corresponding auther: LI Xiao-jiang,E-mail: xiaojiangle.@yahoo.com.cn E-mail:xiaojiangle.@yahoo.com.cn

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摘要： 微RNA(miRNA)在转录后水平调控靶基因的表达。头颈肿瘤中存在多种miRNA的差异表达，其参与细胞发育、增殖、分化、凋亡等一系列重要生物学进程，有望成为诊断治疗头颈肿瘤的有效手段。

Abstract: MicroRNAs (miRNAs) regulate target genes expression in the post-transcriptional levels. There are many kinds of differential expressions of miRNA in head and neck cancer, and the miRNA participate in a series of important biological processes such as cell development, proliferation, differentiation, apoptosis and etc. miRNAsis expected to become an effective means for the diagnosis and treatment of head and neck cancer.