Journal of International Oncology ›› 2017, Vol. 44 ›› Issue (7): 541-543.doi: 10.3760/cma.j.issn.1673-422X.2017.07.016

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Non-coding small RNA and melanoma

Chai Li, Kang Xiaojing   

  1. Graduate School of Xinjiang Medical University; Department of Dermatology and Venereology, People′s Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China
  • Received:2017-02-21 Online:2017-07-08 Published:2017-06-20
  • Contact: Kang Xiaojing E-mail:drkangxj666@163.com
  • Supported by:

    Natural Science Foundation of Xinjiang Uygur Autonomous Region of China (2016D01C101)

Abstract: Non-coding small RNA mainly includes microRNA, small interfering RNA and RNA interacting with PIWI protein. Studies have shown that non-coding small RNA plays an increasingly important role in the epigenetic regulation. Non-coding small RNA is involved in the regulation of gene expression by gene transcription, posttranscription and mRNA translation. Non-coding small RNA is closely related to many human diseases, especially the diagnosis, treatment and prognosis of melanoma.

Key words: Melanoma, Non-coding small RNA