Abstract: Statins can adjust blood fat and cholesterol, and protect the cardiovascular, especially simvastatin, which is used often in clinic. Several recent studies have found that simvastatin can play a positive role in the treatment of multiple tumors by inhibiting tumor growth, invasion and metastasis, and improving the drug resistance of chemotherapeutic agents. Simvastatin may be a potential drug for cancer treatment. It is expected to be a new direction of tumor therapy and prevention.

Key words: Neoplasms, Simvastatin, Targeted therapy