Coiled coil domain containing 6 and tumor

doi:10.3760/cma.j.issn.1673422X.2018.05.006

Journal of International Oncology ›› 2018, Vol. 45 ›› Issue (5): 281-284.doi: 10.3760/cma.j.issn.1673422X.2018.05.006

Previous Articles Next Articles

Coiled coil domain containing 6 and tumor

Sun Dan, Xin Yan

Laboratory of Gastrointestinal Tumor Pathology, Cancer Institute, First Affiliated Hospital of China Medical University, Shenyang 110001, China

Online:2018-05-08 Published:2018-05-23
Contact: Xin Yan E-mail: yxin@cmu.edu.com
Supported by:
National Natural Science Foundation of China (81071650); Science and Technology Planning Project of Liaoning Province of China (2013225585)

Abstract

Abstract: Coiled coil domain containing 6 (CCDC6) is originally found in thyroid papillary carcinoma by participating in RET/PTC1 fusion formation. Studies have shown that CCDC6 plays a vital role in response to DNA damage repair and regulation of cell cycle and apoptosis. As a tumor suppressor, CCDC6 could inhibit tumorgenesis, tumor migration and invasion in thyroid carcinoma, lung cancer, colorectal cancer, prostate cancer and cervical cancer. Intensively study the role and mechanism of CCDC6 in carcinomas will provide a new thought for tumor diagnosis, treatment and clinical prognosis evaluation.

Key words: Neoplasms, Gene fusion, Coiled coil domain containing 6

SUN Dan, XIN Yan. Coiled coil domain containing 6 and tumor[J]. Journal of International Oncology, 2018, 45(5): 281-284.

[1]	Liu Na, Kou Jieli, Yang Feng, Liu Taotao, Li Danping, Han Junrui, Yang Lizhou. Clinical value of serum miR-106b-5p and miR-760 combined with low-dose spiral CT in the diagnosis of early lung cancer [J]. Journal of International Oncology, 2024, 51(6): 321-325.
[2]	Yang Mi, Bie Jun, Zhang Jiayong, Deng Jiaxiu, Tang Zuge, Lu Jun. Analysis of the efficacy and prognosis of neoadjuvant therapy for locally advanced resectable esophageal cancer [J]. Journal of International Oncology, 2024, 51(6): 332-337.
[3]	Yuan Jian, Huang Yanhua. Diagnostic value of Hp-IgG antibody combined with serum DKK1 and sB7-H3 in early gastric cancer [J]. Journal of International Oncology, 2024, 51(6): 338-343.
[4]	Chen Hongjian, Zhang Suqing. Study on the relationship between serum miR-24-3p， H2AFX and clinical pathological features and postoperative recurrence in liver cancer patients [J]. Journal of International Oncology, 2024, 51(6): 344-349.
[5]	Guo Zehao, Zhang Junwang. Role of PFDN and its subunits in tumorigenesis and tumor development [J]. Journal of International Oncology, 2024, 51(6): 350-353.
[6]	Zhang Baihong, Yue Hongyun. Advances in anti-tumor drugs with new mechanisms of action [J]. Journal of International Oncology, 2024, 51(6): 354-358.
[7]	Xu Fenglin, Wu Gang. Research progress of EBV in tumor immune microenvironment and immunotherapy of nasopharyngeal carcinoma [J]. Journal of International Oncology, 2024, 51(6): 359-363.
[8]	Wang Ying, Liu Nan, Guo Bing. Advances of antibody-drug conjugate in the therapy of metastatic breast cancer [J]. Journal of International Oncology, 2024, 51(6): 364-369.
[9]	Zhang Rui, Chu Yanliu. Research progress of colorectal cancer risk assessment models based on FIT and gut microbiota [J]. Journal of International Oncology, 2024, 51(6): 370-375.
[10]	Gao Fan, Wang Ping, Du Chao, Chu Yanliu. Research progress on intestinal flora and non-surgical treatment of the colorectal cancer [J]. Journal of International Oncology, 2024, 51(6): 376-381.
[11]	Liu Jing, Liu Qin, Huang Mei. Prognostic model construction of lung infection in patients with chemoradiotherapy for esophageal cancer based on SMOTE algorithm [J]. Journal of International Oncology, 2024, 51(5): 267-273.
[12]	Yang Lin, Lu Ning, Wen Hua, Zhang Mingxin, Zhu Lin. Study on the clinical relationship between inflammatory burden index and gastric cancer [J]. Journal of International Oncology, 2024, 51(5): 274-279.
[13]	Wang Junyi, Hong Kaibin, Ji Rongjia, Chen Dachao. Effect of cancer nodules on liver metastases after radical resection of colorectal cancer [J]. Journal of International Oncology, 2024, 51(5): 280-285.
[14]	Zhang Ningning, Yang Zhe, Tan Limei, Li Zhenning, Wang Di, Wei Yongzhi. Diagnostic value of cervical cell DNA ploidy analysis combined with B7-H4 and PKCδ for cervical cancer [J]. Journal of International Oncology, 2024, 51(5): 286-291.
[15]	Fu Yi, Ma Chenying, Zhang Lu, Zhou Juying. Research progress of habitat analysis in radiomics of malignant tumors [J]. Journal of International Oncology, 2024, 51(5): 292-297.

Coiled coil domain containing 6 and tumor

PDF

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments