Journal of International Oncology ›› 2017, Vol. 44 ›› Issue (8): 679-681.doi: 10.3760/cma.j.issn.1673422X.2017.09.009

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Dysbiosis of gut microbiota drives cancer development

Zhang Baihong, Yue Hongyun   

  1. Department of Oncology, Lanzhou General Hospital of Lanzhou Military Region, Lanzhou 730050, China
  • Online:2017-09-08 Published:2017-10-31
  • Contact: Zhang Baihong E-mail:bhzhang1999@126.com
  • Supported by:

    Natural Science Foundation of Gansu Province of China (1308RJZA181)

Abstract: Numerous studies support the importance of gut microbiota as environment factors in the development of cancer. The mechanisms that gut microbiota drive certain cancers include impacting immunity, modulating inflammation, inducing DNA damage, producing cancer promoting metabolites and regulating signaling pathway. Microbiomebased therapies provide potential prospects for cancer treatment.

Key words: Neoplasms, Microbiome, Gut microbiota, Tumorigenesis