Effect and mechanism of NF-κB signaling pathway on the biological characteristics of glioma

doi:10.3760/cma.j.issn.1673422X.2016.12.011

Abstract

Abstract: NF-κB signaling pathway is widely present in eukaryotes, and it is involved in many biological processes, such as embryonic development, inflammation, immunity, and tumor development. The abnormal activation of NFκB signaling pathway is closely related to the biological characteristics of glioma. Investigating the role of NFκB signaling pathway in the glioma proliferation, invasion, apoptosis and angiogenesis will provide new ideas and targets for the treatment of glioma.

Key words: Glioma, NF-kappa B, Signal transduction

LIU Jing, WU Yong-Qiang, GUO Geng, WANG Xiao-Gang. Effect and mechanism of NF-κB signaling pathway on the biological characteristics of glioma[J]. Journal of International Oncology, 2016, 43(12): 924-926.

References

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