Journal of International Oncology

Journal of International Oncology ›› 2015, Vol. 42 ›› Issue (11): 845-848.doi: 10.3760/cma.j.issn.1673422X.2015.11.013

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Research status of matrix metalloproteinase9 on metastatic breast cancer

Matrix metalloproteinase9 (MMP9) can promote the invasion and metastasis of breast cancer through various mechanisms. The expressions of MMP9 in the patients with breast cancer are correlated with the prognosis. The higher expression of MMP9 indicates poorer prognosis. It is suggested that the level change of MMP9 pre and post treatment can be used as a reference standard for judging the prognosis and clinical effect.   

  1. Department of Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, China
  • Online:2015-11-08 Published:2015-09-30
  • Contact: Sun Weili; Wang Youqun E-mail:sunweili@medmail.com.cn;wyqfbox@163.com

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Abstract: Matrix metalloproteinase9 (MMP9) can promote the invasion and metastasis of breast cancer through various mechanisms. The expressions of MMP9 in the patients with breast cancer are correlated with the prognosis. The higher expression of MMP9 indicates poorer prognosis. It is suggested that the level change of MMP9 pre and post treatment can be used as a reference standard for judging the prognosis and clinical effect.

Key words: Matrix metalloproteinase 9, Breast neoplasms, Prognosis, Reference standards