Abstract: Triple negative breast cancer (TNBC) is a special subgroup of breast cancer with more aggressive biological behavior and clinicopathological characteristics, and the therapy of TNBC has always been the research difficulty and hot spot. Currently，surgery and adjuvant radiotherapy are still the main method in local treatment, amd the research of traditional chemotherapy and targeted therapy have been made some progress.Meanwhile, new drugs continuously appear in recent years.

Key words: Breast neoplasms, Surgical procedures, Radiotherapy, Drug therapy, Molecular tagerted therapy