Abstract: MicroRNAs (miRNAs) are involved in cell growth, differentiation, apoptosis and tumor occurrence and play an important role in regulation. Many studies show that miRNAs can regulate the expression of target gene, which is associated closely with the occurrence, development, chemosensitivity and prognosis of colorectal cancer. Detection of miRNAs is expected to formulate more detailed individualized chemotherapy for colorectal cancer patients and improve their prognosis.

Key words: MicroRNAs, Colorectal neoplasms, Drug resistangce, neoplasm, Drug therapy, Prognosis