Research progress on exosomederived noncoding RNAs in liquid biopsy of hepatocelluar carcinoma

doi:10.3760/cma.j.issn.1673-422X.2019.06.014

Abstract

Abstract: Exosomes contain ample non-coding RNAs， which mainly function as regulating gene expression and play key roles in the occurrence and development of hepatocellular carcinoma. Exosomal non-coding RNAs are expected to become a new biopsy marker for hepatocellular carcinoma, providing a new means for early diagnosis and early treatment of hepatocellular carcinoma.Although the clinical application of exosomal noncoding RNAs is still insufficient at present, exosomal noncoding RNAs will play an increasingly important role in the diagnosis, personalized treatment and prognosis evaluation of hepatocellular carcinoma with the deepening of research.

Key words: Liver neoplasms, Liquid biopsy, Exosomes, Non-coding RNA

Zhang Fangyong, Wu Fan. Research progress on exosomederived noncoding RNAs in liquid biopsy of hepatocelluar carcinoma[J]. Journal of International Oncology, 2019, 46(6): 378-381.

References

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