Roles of exosomes in tumor formation, diagnosis and treatment

doi:10.3760/cma.j.issn.1673-422X.2018.12.008

Abstract

Abstract: Exosomes are subcellular membrane structures secreted by both normal cells and tumor cells. They contain a variety of specific microRNAs (miRNAs) and signaling molecules, and have important research value in tumorigenesis, tumor diagnostic classification and immunotherapy. The effect of exosomes on tumorigenesis is a doubleedged sword, and the miRNAs act as molecular markers and contribute to classify morphologically intractable tumors such as glioblastoma. In antineoplastic therapy, exosomes can be used as drug carriers or induce a new type of immunotherapy through their own characteristics.

Key words: Neoplasms, Diagnosis, Immunotherapy, Exosomes

Yang Xin, Meng Bin. Roles of exosomes in tumor formation, diagnosis and treatment[J]. Journal of International Oncology, 2018, 45(12): 739-742.

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