Journal of International Oncology ›› 2018, Vol. 45 ›› Issue (10): 624-626.doi: 10.3760/cma.j.issn.1673-422X.2018.10.010

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Complexities in necroptosis and tumor

Ding Jinye, Cheng Zhongping   

  1. Department of Gynecology and Obstetrics, Tenth People′s Hospital Affiliated to Tongji University, Shanghai 200072, China
  • Received:2018-04-10 Online:2018-10-08 Published:2018-12-21
  • Contact: Cheng Zhongping E-mail:mdcheng18@tongji.edu.cn

Abstract: The complexities in necroptosis are pivotal signal molecules in the pathway. Its formation is regulated by a series of factors such as necrosome and ripoptosome. The studies have found that the complexities in necroptosis are closely related to multiple neoplasms, such as pancreatic ductal adenocarcinoma and glioma. Further study on the regulatory mechanism of them will provide a new idea for molecular cancer therapeutics.

Key words: Neoplasms, Complexities in necroptosis