[1] 黄志敏, 吴一龙. 非小细胞肺癌的BRAF基因突变及其临床意义[J]. 中国肺癌杂志, 2012, 15(3): 183-186. DOI: 10.3779/j.issn.1009-3419.2012.03.09.
[2] Li S, Li L, Zhu Y, et al. Coexistence of EGFR with KRAS, or BRAF, or PIK3CA somatic mutations in lung cancer: a comprehensive mutation profiling from 5 125 Chinese cohorts[J]. Br J Cancer, 2014, 110(11): 2812-2820. DOI: 10.1038/bjc.2014.210.
[3] Cardarella S, Ogino A, Nishino M, et al. Clinical, pathologic, and biologic features associated with BRAF mutations in non-small cell lung cancer[J]. Clin Cancer Res, 2013, 19(16): 4532-4540. DOI: 10.1158/10780432.CCR-13-0657.
[4] Marchetti A, Felicioni L, Malatesta S, et al. Clinical features and outcome of patients with non-small cell lung cancer harboring BRAF mutations[J]. J Clin Oncol, 2011, 29(26): 3574-3579. DOI: 10.1200/JCO.2011.35.9638.
[5] Chen D, Zhang LQ, Huang IF, et al. BRAF mutations in patients with non-small cell lung cancer, a systematic review and metaanalysis[J]. PLoS One, 2014, 9(6): e101354.DOI: 10.1371/journal.pone.0101354.
[6] Brustugun OT, Khattak AM, Tromborg AK, et al. BRAFmutations in non-small cell lung cancer[J]. Lung Cancer, 2014, 84(1): 36-38.DOI: 10.1016/j.lungcan.2014.01.023.
[7] Alrifai D, Popat S, Ahmed M, et al. A rare case of squamous cell carcinoma of the lung harbouring ALK and BRAF activating mutations[J]. Lung Cancer, 2013, 80(3): 339-340.DOI: 10.1016/j.lungcan.2013.02.002.
[8] Ohashi K, Sequist LV, Arcila ME, et al. Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1[J]. Proc Natl Acad Sci USA, 2012, 109(31): E2127-2133. DOI: 10.1073/pnas.1203530109.
[9] Robinson S, O′Shaughnessy J, CL C, et al. BRAF V600Emutated lung adenocarcinoma with metastases to the brain responding to treatment with vemurafenib[J]. Lung Cancer, 2014, 85(2): 326-330.DOI: 10.1016/j.lungcan.2014.05.009.
[10] Gautschi O, Milia J, Cabarrou B, et al. Targeted therapy for patients with BRAFmutant lung cancer: results from the european EURAF cohort[J]. J Thorac Oncol, 2015, 10(10): 1451-1457.DOI: 10.1097/JTO.0000000000000625.
[11]Gibney G, Zager J. Clinical development of dabrafenib in BRAF mutant melanoma and other malignancies[J]. Expert Opin Drug Metab Toxicol, 2013, 9(7): 893-899.DOI: 10.1517/17425255.2013.794220.
[12]Planchard D, Kim TM, Mazieres J, et al. Dabrafenib in patient with BRAF V600Emutant advanced nonsmall cell lung cancer(NSCLC): a multicenter, open-label, phase Ⅱ trial(BRF113928)[J]. Ann Oncol, 2014, 25(suppl 4): v1-v41.
[13]Schmid S, Siano M, Joerger M, et al. Response to dabrafenib after progression on vemurafenib in a patient with advanced BRAF V600Emutant bronchial adenocarcinoma[J]. Lung Cancer, 2015, 87(1): 85-87.DOI: 10.1016/j.lungcan.2014.11.008.
[14]Kim ES, Herbst RS, Wistuba II, et al. The BATTLE trial: personalizing therapy for lung cancer[J]. Cancer Discov, 2011, 1(1): 4453. DOI: 10.1158/21598274.CD-10-0010.
[15]Sereno M, Moreno V, Moreno Rubio J, et al. A significant response to sorafenib in a woman with advanced lung adenocarcinoma and a BRAF non-V600 mutation[J]. Anticancer Drugs, 2015, 26(9):1004-1007.DOI: 10.1097/CAD.0000000000000277.
[16]Rudin CM, Hong K, Streit M. Molecular characterization of acquired resistance to the BRAF inhibitor dabrafenib in a patient with BRAFmutant non-small cell lung cancer[J]. J Thorac Oncol, 2013, 8(5): e41-42. DOI: 0.1097/JTO.0b013e31828bb1b3
[17]Paraiso KH, Fedorenko IV, Cantini LP, et al. Recovery of phospho-ERK activity allows melanoma cells to escape from BRAF inhibitor therapy[J]. Br J Cancer, 2010, 102(12): 1724-1730.DOI: 10.1038/sj.bjc.6605714.
[18]Joshi M, Rice SJ, Liu X, et al. Trametinib with or without vemurafenib in BRAF mutated non-small cell lung cancer[J]. PLoS One, 2015, 10(2): e0118210.DOI: 10.1371/journal.pone.0118210.
[19] 耿睿, 潘莉, 宋霞. 程序性死亡配体-1及其抑制剂在非小细胞肺癌中的研究进展[J]. 国际肿瘤学杂志, 2015, 42(8): 628-630. DOI: 103760/cma.j.issn.1673422X.2015.08.019 |