Journal of International Oncology ›› 2016, Vol. 43 ›› Issue (6): 468-471.doi: 10.3760/cma.j.issn.1673-422X.2016.06.019

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Advances of cancer stem cell markers in colorectal cancer

Liu Liguo, Yan Xuebing, Shan Zezhi, Jin Zhiming   

  1. Department of General Surgery, Affiliated Sixth People′s Hospital, Shanghai Jiaotong University, Shanghai 200233, China
  • Received:2015-10-15 Online:2016-06-08 Published:2016-04-27
  • Contact: Jin Zhiming E-mail:jzmgyp@aliyun.com

Abstract: Cancer stem cells (CSCs) markers are specific molecules to identify CSCs. Recent findings demonstrate that CSCs markers associated with colorectal cancer mainly include CD133, CD29, CD166, CD44, Nanog, etc. These markers can take park in the initiation and progression of cancers by various molecular mechanisms, which have the potential to be used as therapeutic targets as well as prognostic indicators.

Key words: Colorectal neoplasms, Neoplastic stem cells, Tumor markers, biological, Prognosis