Journal of International Oncology ›› 2016, Vol. 43 ›› Issue (5): 356-359.doi: 10.3760/cma.j.issn.1673-422X.2016.05.009

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Molecular mechanism of tumor associated hypercoagulability

Zhang Xue, Jiang Da, Li Ying   

  1. Department of Oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China
  • Online:2016-05-08 Published:2016-04-07
  • Contact: Jiang Da E-mail:jiangda139@163.com

Abstract: The process of tumorigenesis, local invasion and distant metastasis will produce a series of molecular changes, these genetic mutation or abnormal expression of molecules play a promoting role in hypercoagulation. At the same time, hypercoagulation also increases the risk of tumor progression. It is important to understand their specific processes and the molecular role, and it can provide theoretical basis for better management of patients, and has significance for developing more effective and security new anticlotting drugs.

Key words: Neoplasms, Blood coagulation, Molecular mechanism