Journal of International Oncology ›› 2016, Vol. 43 ›› Issue (1): 42-44.doi: 10.3760/cma.j.issn.1673-422X.2016.01.012

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High risk factors related to central lymph node metastasis in papillary thyroid microcarcinoma

Li Yao, Wang Shengying   

  1. Department of Head and Neck Surgery, Anhui Provincial Cancer Hospital, Hefei 230030, China
  • Received:2015-05-22 Online:2016-01-08 Published:2015-12-03
  • Contact: Wang Shengying E-mail:wangshengying61@163.com

Abstract: In recent years, a large number of studies have found that central lymph node metastasis of the papillary thyroid microcarcinoma (PTMC) is significantly related with some risk factors. These high risk factors include age below 45 years old, BRAF gene mutation, vascular epithelial growth factorC high expression, tumor diameter≥5 mm, multifocal and bilateral tumor, thyroid capsule invasion and so on. These high risk factors involve in disease process, and interact with each other. The studies of the high risk factors can help us to predict the risk of central lymph node metastasis in the patients with PTMC, thus to effectively guide the patients′ treatment.

Key words: Thyroid neoplasms, Lymph nodes, Risk factors