Journal of International Oncology ›› 2015, Vol. 42 ›› Issue (12): 924-927.doi: 10.3760/cma.j.issn.1673-422X.2015.12.011

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Applications of the biomakerdetection technology guiding neoadjuvant therapy for advanced esophageal cancer

Li Chen, Cheng Yufeng   

  1. Department of Radiation Oncology, Qilu Hospital of Shandong Univeristy, Ji′nan 250012, China
  • Online:2015-12-08 Published:2015-11-10
  • Contact: Cheng Yufeng E-mail:qlcyfsdu@163.com

Abstract: At present, the technology to predict the response to neoadjuvant therapy with biomakers has been widely used in clinical practice. The approaches of biomarkers detection are various, including immunohistochemistry, detection of serum biomarkers conventional blood tests, gene expression profile analysis, single nucleotide polymorphisms, miRNAs, proteomics analysis. With the development of biotechnology, the technology of biomarkers detection is expected to become effective means in assessment of adjuvant therapy, risk, prognosis and individualization in esophageal cancer treatment.

Key words: Esophageal neoplasms, Biological makers, Neoadjuvant therapy