Gemcitabine in combination with chemotherapy in the treatment of recurrent or metastatic breast cancer

doi:10.3760/cma.j.issn.1673-422X.2015.10.014

Abstract

Abstract: Gemcitabine based chemotherapy is effective in recurrent or metastatic breast cancer. Besides the 3 week regimen in combination with paclitaxel, individualized treatments are also applied to combine gemcitabine with other agents such as docetaxel or platinum, or to administer by different frequency or dose, or to continuously maintain on the treatment as an extension to front line. It is demonstrated that gemcitabine in combination with taxanes can obtain survival benefit, largely in patients with visceral metastasis or hormone receptor negative. Initial evidence has also supported the feasibility of continuous maintenance. Finally, gemcitabine in combination with cisplatin is a better option for the metastatic triple negative breast cancer.

Key words: Breast neoplasms, Drug therapy, Gemcitabine

Tong Zhongsheng, Xu Cong, Wang Jin. Gemcitabine in combination with chemotherapy in the treatment of recurrent or metastatic breast cancer[J]. Journal of International Oncology, 2015, 42(10): 769-772.

References

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