Journal of International Oncology ›› 2015, Vol. 42 ›› Issue (6): 448-451.doi: 10.3760/cma.j.issn.1673-422X.2015.06.013

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Effect of tumor radiotherapy on the immune response

Kong Yuehong, Ding Jiping, Tu Wenyong   

  1. Department of Oral & Maxillofacial Head & Neck Oncology, Shanghai Ninth People′s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200011, China
  • Received:2014-11-05 Online:2015-06-08 Published:2015-05-31
  • Contact: Tu Wenyong E-mail:tu4you@163.com

Abstract: Tumor radiation therapy (RT) can affect the immune system. Latest studies show that appropriate RT can activate the immune system through regulating tumor microenvironment, activating immune cells and releasing danger signals, and can produce bystander or abscopal effect. With the development of clinical biomarkers research and clinical trials about RT combined with immunotherapy, it is expected to change the traditional pattern of tumor treatment.

Key words: Radiotherapy, Neoplasms, Immunotherapy, Bystander effect