Journal of International Oncology ›› 2014, Vol. 41 ›› Issue (12): 918-921.doi: 10.3760/cma.j.issn.1673-422X.2014.12.013

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Research progress of SPARC in esophageal cancer

  

  1. Department of Oncology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China
  • Online:2014-12-24 Published:2015-02-02
  • Contact: Corresponding author: Yang Shujun,Email: nkyang@126.com

Abstract: Secreted protein acidic and rich in cysteine (SPARC) is expressed in esophageal cancer abnormally. On the one hand, recent studies show that high SPARC expression is correlated with progression and metastasis of esophageal cancer. On the other hand, high SPARC expression increases chemosensitivity and improves shortterm efficacy in patients.

Key words: Osteonectin, Esophageal neoplasms, Prognosis