Journal of International Oncology ›› 2014, Vol. 41 ›› Issue (12): 884-887.doi: 10.3760/cma.j.issn.1673-422X.2014.12.002

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The role of microRNAs in breast cancer stem cells

  

  1. Department of General Surgery, Affiliated Jiangsu Cancer Hospital, Nanjing Medical University, Nanjing 210009, China
  • Online:2014-12-24 Published:2015-02-02
  • Contact: Tang Jinhai, Email: lfmcfdd@126.com

Abstract: The role of microRNAs in breast cancer stem cellsMao Changfei, Wu Jianzhong, Tang Jinhai. Corresponding author:【Abstract】Cancer stem cells are a kind of cancer cell group with the ability of selfrenewal and various diferentiation potentials. Recent studies have implicated that they play a significant role in tumor formation, metastasis, resistance to anticancer therapies and cancer recurrence. Many studies show that microRNAs are involved in the maintenance, growth and behavior of breast cancer stem cells(BCSCs), paving a new way for diagnosis, prognosis and therapy of breast cancer.

Key words: MicroRNAs, Neoplastic stem cells, Breast neoplasms